Scientists establish a new class of anti-diabetic compound
In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique...
View ArticleDesigning a new drug for chronic pain
(Medical Xpress)—Scientists at the University of Liverpool and the Royal Liverpool University Hospital have been awarded £1.4 million to design a new drug for the treatment of chronic pain.
View ArticleMedicinal toothbrush tree yields antibiotic to treat TB in new way
A compound from the South African toothbrush tree inactivates a drug target for tuberculosis in a previously unseen way.
View ArticleCircadian rhythms can be modified for potential treatment of disorders
(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds...
View ArticleXL-184 (Cabozantinib) goes 12-for-12 in colorectal cancer explants
The novel c-MET and VEGFR2 inhibitor, XL-184 (Cabozantinib), resulted in a significant decrease in tumor growth in 12 out of 12 colorectal cancer (CRC) patient-derived explants, with 8 of the explants...
View ArticleFish oil found to help serious pregnancy complications
Taking fish oil during pregnancy could limit the effects of serious complications such as gestational diabetes, pre-eclampsia and miscarriage as well as enhancing fetal growth, according to researchers...
View ArticleStem cell research paves way for progress on dealing with Fragile X retardation
Researchers at the Hebrew University of Jerusalem have achieved, for the first time, the generation of neuronal cells from stem cells of Fragile X patients. The discovery paves the way for research...
View ArticleStudy: Statins may stem tumor growth
(Medical Xpress)—One of the world's top selling drugs potentially also acts against the growth of new lymphatic vessels, with potential implications for cancer therapy. This surprising finding was...
View ArticleStem cell research reveals clues to brain disease
(Medical Xpress)—The development of new drugs for improving treatment of Alzheimer's and Parkinson's disease is a step closer after recent research into how stem cells migrate and form circuits in the...
View ArticleResearchers hope to forecast novel psychoactive substance use by the public
The use of novel psychoactive substances – synthetic compounds with stimulant or hallucinogenic effects – is on the rise. The diversity and breadth of these substances has led policymakers, law...
View ArticleResearchers to explore ability of compounds to protect brain against HIV...
Antiretroviral drugs can greatly increase life expectancy for patients infected with HIV, the AIDS-causing virus, but one thing the drugs cannot do is completely eliminate the virus from the body....
View ArticleNeuronal structures associated with memory sprout in response to novel molecules
Chemists at the University of California San Diego have designed a set of molecules that promote microscopic, anatomical changes in neurons associated with the formation and retention of memories....
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